ST14 antibody (AA 10-59)

Catalog No. ABIN1534221

This Rabbit Polyclonal antibody specifically detects ST14 in WB, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ST14 antibody (AA 10-59) (ABIN1534221)

Target: ST14 (Suppression of Tumorigenicity 14 (ST14))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ST14 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-ST14 Antibody

Binding Specificity: AA 10-59

Purpose: Matriptase Antibody

Specificity: Matriptase Polyclonal Antibody detects endogenous levels of Matriptase protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ST14. AA range:10-59

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ST14

Target: ST14 (Suppression of Tumorigenicity 14 (ST14))

Alternative Name: ST14

Background:

Synonyms: ST14, PRSS14, SNC19, TADG15, Suppressor of tumorigenicity 14 protein, Matriptase, Membrane-type serine protease 1, MT-SP1, Prostamin, Serine protease 14, Serine protease TADG-15, Tumor-associated differentially-expressed gene 15 protein

Background: The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. [provided by RefSeq, Jul 2008],

Gene Name: ST14

Protein Name: Suppressor of tumorigenicity 14 protein

Molecular Weight: 94 kDa

Gene ID: 6768

OMIM: 606797

UniProt: Q9Y5Y6