14-3-3 eta antibody (AA 51-100)

Catalog No. ABIN1534234

The Rabbit Polyclonal anti-14-3-3 eta antibody is suitable to detect 14-3-3 eta in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for 14-3-3 eta antibody (AA 51-100) (ABIN1534234)

Target: 14-3-3 eta (YWHAH)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This 14-3-3 eta antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-14-3-3 eta Antibody

Binding Specificity: AA 51-100

Purpose: 14-3-3 η Antibody

Specificity: 14-3-3 η Polyclonal Antibody detects endogenous levels of 14-3-3 η protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human 14-3-3 eta. AA range:51-100

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for 14-3-3 eta

Target: 14-3-3 eta (YWHAH)

Alternative Name: 14-3-3 eta

Background:

Synonyms: YWHAH; YWHA1; 14-3-3 protein eta; Protein AS1

Background: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009],

Gene Name: YWHAH

Protein Name: 14-3-3 protein eta

Molecular Weight: 28 kDa

Gene ID: 7533

OMIM: 113508

UniProt: Q04917

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, C21-Steroid Hormone Metabolic Process, Myometrial Relaxation and Contraction