Cadherin-16 antibody (AA 780-829)

Catalog No. ABIN1534285

The Rabbit Polyclonal anti-Cadherin-16 antibody is suitable to detect Cadherin-16 in samples from Human, Mouse and Rat. It has been validated for IHC, WB, IF and ELISA.

Quick Overview for Cadherin-16 antibody (AA 780-829) (ABIN1534285)

Target: Cadherin-16 (CDH16)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin-16 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), ELISA

Product Details anti-Cadherin-16 Antibody

Binding Specificity: AA 780-829

Purpose: Cadherin-16 Antibody

Specificity: Cadherin-16 Polyclonal Antibody detects endogenous levels of Cadherin-16 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CDH16. AA range:780-829

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Cadherin-16

Target: Cadherin-16 (CDH16)

Alternative Name: CDH16

Background:

Synonyms: CDH16, Cadherin-16, Kidney-specific cadherin, Ksp-cadherin

Background: This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011],

Gene Name: CDH16

Protein Name: Cadherin-16

Molecular Weight: 89 kDa

Gene ID: 1014

OMIM: 603118

UniProt: O75309