Cadherin 20 antibody (AA 111-160)

Catalog No. ABIN1534289

The Rabbit Polyclonal anti-Cadherin 20 antibody (ABIN1534289) specifically detects Cadherin 20 in IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Cadherin 20 antibody (AA 111-160) (ABIN1534289)

Target: Cadherin 20 (CDH20)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 20 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Cadherin 20 Antibody

Binding Specificity: AA 111-160

Purpose: Cadherin-20 Antibody

Specificity: Cadherin-20 Polyclonal Antibody detects endogenous levels of Cadherin-20 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CDH20. AA range:111-160

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Cadherin 20

Target: Cadherin 20 (CDH20)

Alternative Name: CDH20

Background:

Synonyms: CDH20, CDH7L3, Cadherin-20

Background: This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq, Jul 2008],

Gene Name: CDH20

Protein Name: Cadherin-20

Molecular Weight: 89 kDa

Gene ID: 28316

OMIM: 605807

UniProt: Q9HBT6