CCR4 antibody (AA 211-260)

Catalog No. ABIN1534310

The Rabbit Polyclonal anti-CCR4 antibody (ABIN1534310) specifically detects CCR4 in ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CCR4 antibody (AA 211-260) (ABIN1534310)

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR4 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-CCR4 Antibody

Binding Specificity: AA 211-260

Purpose: CKR-4 Antibody

Specificity: CKR-4 Polyclonal Antibody detects endogenous levels of CKR-4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CCR4. AA range:211-260

Isotype: IgG

Application Details

Application Notes: IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CCR4

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Alternative Name: CCR4

Background:

Synonyms: CCR4, CMKBR4, C-C chemokine receptor type 4, C-C CKR-4, CC-CKR-4, CCR-4, CCR4, K5-5, CD antigen CD194

Background: The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. [provided by RefSeq, Jul 2008],

Gene Name: CCR4

Protein Name: C-C chemokine receptor type 4

Molecular Weight: 41 kDa

Gene ID: 1233

OMIM: 604836

UniProt: P51679