CDC16 antibody (AA 181-230)

Catalog No. ABIN1534316

The Rabbit Polyclonal anti-CDC16 antibody (ABIN1534316) specifically detects CDC16 in WB, IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CDC16 antibody (AA 181-230) (ABIN1534316)

Target: CDC16 (Cell Division Cycle 16 Homolog (S. Cerevisiae) (CDC16))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC16 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-CDC16 Antibody

Binding Specificity: AA 181-230

Purpose: Cdc16 Antibody

Specificity: Cdc16 Polyclonal Antibody detects endogenous levels of Cdc16 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human APC6. AA range:181-230

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CDC16

Target: CDC16 (Cell Division Cycle 16 Homolog (S. Cerevisiae) (CDC16))

Alternative Name: APC6

Background:

Synonyms: CDC16, ANAPC6, Cell division cycle protein 16 homolog, Anaphase-promoting complex subunit 6, APC6, CDC16 homolog, CDC16Hs, Cyclosome subunit 6

Background: The protein encoded by this gene functions as a protein ubiquitin ligase and is a component of the multiprotein APC complex. The APC complex is a cyclin degradation system that governs exit from mitosis by targeting cell cycle proteins for degredation by the 26S proteasome. Each component protein of the APC complex is highly conserved among eukaryotic organisms. This protein, and other APC complex proteins, contain a tetratricopeptide repeat (TPR) domain, a protein domain that is often involved in protein-protein interactions and the assembly of multiprotein complexes. Multiple alternatively spliced transcript variants, encoding distinct proteins, have been identified. [provided by RefSeq, Jan 2016],

Gene Name: CDC16

Protein Name: Cell division cycle protein 16 homolog

Molecular Weight: 71 kDa

Gene ID: 8881

OMIM: 603461

UniProt: Q13042

Pathways: Regulation of Actin Filament Polymerization