COX17 antibody (AA 1-50)

Catalog No. ABIN1534365

This Rabbit Polyclonal antibody specifically detects COX17 in ELISA, IHC, WB and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for COX17 antibody (AA 1-50) (ABIN1534365)

Target: COX17 (COX17 Cytochrome C Oxidase Assembly Protein 17 (COX17))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX17 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-COX17 Antibody

Binding Specificity: AA 1-50

Purpose: COX17 Antibody

Specificity: COX17 Polyclonal Antibody detects endogenous levels of COX17 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human COX17. AA range:1-50

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for COX17

Target: COX17 (COX17 Cytochrome C Oxidase Assembly Protein 17 (COX17))

Alternative Name: COX17

Background:

Synonyms: COX17, Cytochrome c oxidase copper chaperone

Background: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92 % amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13. [provi

Gene Name: COX17

Protein Name: Cytochrome c oxidase copper chaperone

Molecular Weight: 6 kDa

Gene ID: 10063

OMIM: 604813

UniProt: Q14061