COX7S/A2 (AA 1-50) antibody

Catalog No. ABIN1534371

This Rabbit Polyclonal antibody specifically detects COX7S/A2 in ELISA, IHC, WB and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for COX7S/A2 (AA 1-50) antibody (ABIN1534371)

Target: COX7S/A2

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Product Details

Binding Specificity: AA 1-50

Purpose: COX7a2/3 Antibody

Specificity: COX7a2/3 Polyclonal Antibody detects endogenous levels of COX7a2/3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human COX7S/A2. AA range:1-50

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details

Target: COX7S/A2

Background:

Synonyms: COX7A2P2, COX7A3, COX7AL2, COX7AP2, Putative cytochrome c oxidase subunit 7A3, mitochondrial, Cytochrome c oxidase subunit VIIa 3, COX7A2, COX7AL, Cytochrome c oxidase subunit 7A2, mitochondrial, Cytochrome c oxidase subunit VIIa-liver/hear

Background: Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14.

Gene Name: COX7A2/COX7A2P2

Protein Name: Cytochrome c oxidase subunit 7A2/3 mitochondrial

Molecular Weight: 11 kDa

Gene ID: 1347

OMIM: 123997

UniProt: O60397