Laminin beta 3 antibody (AA 671-720)

Catalog No. ABIN1534458

This Rabbit Polyclonal antibody specifically detects Laminin beta 3 in IHC, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Laminin beta 3 antibody (AA 671-720) (ABIN1534458)

Target: Laminin beta 3 (LAMB3) (Laminin, beta 3 (LAMB3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Laminin beta 3 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Laminin beta 3 Antibody

Binding Specificity: AA 671-720

Purpose: Laminin β-3 Antibody

Specificity: Laminin β-3 Polyclonal Antibody detects endogenous levels of Laminin β-3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human LAMB3. AA range:671-720

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Laminin beta 3

Target: Laminin beta 3 (LAMB3) (Laminin, beta 3 (LAMB3))

Alternative Name: LAMB3

Background:

Synonyms: LAMB3, LAMNB1, Laminin subunit beta-3, Epiligrin subunit bata, Kalinin B1 chain, Kalinin subunit beta, Laminin B1k chain, Laminin-5 subunit beta, Nicein subunit beta

Background: The product encoded by this gene is a laminin that belongs to a family of basement membrane proteins. This protein is a beta subunit laminin, which together with an alpha and a gamma subunit, forms laminin-5. Mutations in this gene cause epidermolysis bullosa junctional Herlitz type, and generalized atrophic benign epidermolysis bullosa, diseases that are characterized by blistering of the skin. Multiple alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008],

Gene Name: LAMB3

Protein Name: Laminin subunit beta-3

Molecular Weight: 129 kDa

Gene ID: 3914

OMIM: 150310

UniProt: Q13751

Pathways: Brown Fat Cell Differentiation