LAMC3 antibody (AA 1361-1410)

Catalog No. ABIN1534460

The Rabbit Polyclonal anti-LAMC3 antibody (ABIN1534460) specifically detects LAMC3 in WB, IHC, ELISA and IF. The antibody is reactive with Mouse and Human samples.

Quick Overview for LAMC3 antibody (AA 1361-1410) (ABIN1534460)

Target: LAMC3 (Laminin, gamma 3 (LAMC3))

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAMC3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-LAMC3 Antibody

Binding Specificity: AA 1361-1410

Purpose: Laminin γ-3 Antibody

Specificity: Laminin γ-3 Polyclonal Antibody detects endogenous levels of Laminin γ-3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human LAMC3. AA range:1361-1410

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for LAMC3

Target: LAMC3 (Laminin, gamma 3 (LAMC3))

Alternative Name: LAMC3

Background:

Synonyms: LAMC3, Laminin subunit gamma-3, Laminin-12 subunit gamma, Laminin-14 subunit gamma, Laminin-15 subunit gamma

Background: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biol

Gene Name: LAMC3

Protein Name: Laminin subunit gamma-3

Molecular Weight: 172 kDa

Gene ID: 10319

OMIM: 604349

UniProt: Q9Y6N6