RAD21 antibody (AA 521-570)

Catalog No. ABIN1534487

The Rabbit Polyclonal anti-RAD21 antibody (ABIN1534487) specifically detects RAD21 in WB, IF, ELISA and IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for RAD21 antibody (AA 521-570) (ABIN1534487)

Target: RAD21 (RAD21 Homolog (RAD21))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD21 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (IHC)

Product Details anti-RAD21 Antibody

Binding Specificity: AA 521-570

Purpose: Rad21 Antibody

Specificity: Rad21 Polyclonal Antibody detects endogenous levels of Rad21 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human RAD21. AA range:521-570

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for RAD21

Target: RAD21 (RAD21 Homolog (RAD21))

Alternative Name: RAD21

Background:

Synonyms: RAD21, HR21, KIAA0078, NXP1, Double-strand-break repair protein rad21 homolog, hHR21, Nuclear matrix protein 1, NXP-1, SCC1 homolog

Background: The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq, Jul 2008],

Gene Name: RAD21

Protein Name: Double-strand-break repair protein rad21 homolog

Molecular Weight: 71 kDa

Gene ID: 5885

OMIM: 606462

UniProt: O60216

Pathways: Positive Regulation of Endopeptidase Activity