MRPS35 antibody (AA 211-260)

Catalog No. ABIN1534510

The Rabbit Polyclonal anti-MRPS35 antibody is suitable to detect MRPS35 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for MRPS35 antibody (AA 211-260) (ABIN1534510)

Target: MRPS35 (Mitochondrial Ribosomal Protein S35 (MRPS35))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS35 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MRPS35 Antibody

Binding Specificity: AA 211-260

Purpose: MRP-S35 Antibody

Specificity: MRP-S35 Polyclonal Antibody detects endogenous levels of MRP-S35 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MRPS35. AA range:211-260

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MRPS35

Target: MRPS35 (Mitochondrial Ribosomal Protein S35 (MRPS35))

Alternative Name: MRPS35

Background:

Synonyms: MRPS35, MRPS28, HDCMD11P, MDS023, PSEC0213, 28S ribosomal protein S35, mitochondrial, MRP-S35, S35mt, 28S ribosomal protein S28, mitochondrial, MRP-S28, S28mt

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.This gene encodes a 28S subunit protein that has had confusing nomenclature in the literature. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on

Gene Name: MRPS35

Protein Name: 28S ribosomal protein S35 mitochondrial

Molecular Weight: 36 kDa

Gene ID: 60488

OMIM: 611995

UniProt: P82673