MRPL21 antibody (AA 131-180)

Catalog No. ABIN1534524

This Rabbit Polyclonal antibody specifically detects MRPL21 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for MRPL21 antibody (AA 131-180) (ABIN1534524)

Target: MRPL21 (Mitochondrial Ribosomal Protein L21 (MRPL21))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL21 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MRPL21 Antibody

Binding Specificity: AA 131-180

Purpose: MRP-L21 Antibody

Specificity: MRP-L21 Polyclonal Antibody detects endogenous levels of MRP-L21 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MRPL21. AA range:131-180

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MRPL21

Target: MRPL21 (Mitochondrial Ribosomal Protein L21 (MRPL21))

Alternative Name: MRPL21

Background:

Synonyms: MRPL21, 39S ribosomal protein L21, mitochondrial, L21mt, MRP-L21

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.This gene encodes a 39S subunit protein. Multiple transcript variants encoding different isoforms were identified through sequence analysis although some may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Jul 2008],

Gene Name: MRPL21

Protein Name: 39S ribosomal protein L21 mitochondrial

Molecular Weight: 23 kDa

Gene ID: 219927

OMIM: 611834

UniProt: Q7Z2W9