MRPL46 antibody (AA 111-160)

Catalog No. ABIN1534532

The Rabbit Polyclonal anti-MRPL46 antibody (ABIN1534532) specifically detects MRPL46 in WB, ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MRPL46 antibody (AA 111-160) (ABIN1534532)

Target: MRPL46 (Mitochondrial Ribosomal Protein L46 (MRPL46))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL46 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MRPL46 Antibody

Binding Specificity: AA 111-160

Purpose: MRP-L46 Antibody

Specificity: MRP-L46 Polyclonal Antibody detects endogenous levels of MRP-L46 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MRPL46. AA range:111-160

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MRPL46

Target: MRPL46 (Mitochondrial Ribosomal Protein L46 (MRPL46))

Alternative Name: MRPL46

Background:

Synonyms: MRPL46, C15orf4, LIECG2, 39S ribosomal protein L46, mitochondrial, L46mt, MRP-L46, P2ECSL

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008],

Gene Name: MRPL46

Protein Name: 39S ribosomal protein L46 mitochondrial

Molecular Weight: 31 kDa

Gene ID: 26589

OMIM: 611851

UniProt: Q9H2W6