RPS3 antibody (AA 171-220)

Catalog No. ABIN1534546

The Rabbit Polyclonal anti-RPS3 antibody is suitable to detect RPS3 in samples from Human, Mouse and Rat. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for RPS3 antibody (AA 171-220) (ABIN1534546)

Target: RPS3 (Ribosomal Protein S3 (RPS3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPS3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-RPS3 Antibody

Binding Specificity: AA 171-220

Purpose: Ribosomal Protein S3 Antibody

Specificity: Ribosomal Protein S3 Polyclonal Antibody detects endogenous levels of Ribosomal Protein S3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human RPS3. AA range:171-220

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for RPS3

Target: RPS3 (Ribosomal Protein S3 (RPS3))

Alternative Name: RPS3

Background:

Synonyms: RPS3, OK/SW-cl.26, 40S ribosomal protein S3

Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins.This gene encodes a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated. The protein belongs to the S3P family of ribosomal proteins. Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage. The protein appears to be located in both the cytoplasm and nucleus but not in the nucleolus. Higher levels of expression of this gene in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed. This gene is co-transcribed with the small nucleolar RNA genes U15A and

Gene Name: RPS3

Protein Name: 40S ribosomal protein S3

Molecular Weight: 26 kDa

Gene ID: 6188

OMIM: 600454

UniProt: P23396

Pathways: Positive Regulation of Endopeptidase Activity