RPL7 antibody (AA 199-248)

Catalog No. ABIN1534577

The Rabbit Polyclonal anti-RPL7 antibody (ABIN1534577) specifically detects RPL7 in WB, IHC, ELISA and IF. The antibody is reactive with Human, Mouse, Rat and Cat samples.

Quick Overview for RPL7 antibody (AA 199-248) (ABIN1534577)

Target: RPL7 (Ribosomal Protein L7 (RPL7))

Reactivity: Human, Mouse, Rat, Cat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPL7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-RPL7 Antibody

Binding Specificity: AA 199-248

Purpose: Ribosomal Protein L7 Antibody

Specificity: Ribosomal Protein L7 Polyclonal Antibody detects endogenous levels of Ribosomal Protein L7 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human RPL7. AA range:199-248

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for RPL7

Target: RPL7 (Ribosomal Protein L7 (RPL7))

Alternative Name: RPL7

Background:

Synonyms: RPL7, 60S ribosomal protein L7

Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins.This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins. It contains an N-terminal basic region-leucine zipper (BZIP)-like domain and the RNP consensus submotif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA, with a preference for 28S rRNA and mRNA. The protein can inhibit cell-free translation of mRNAs, suggesting that it plays a regulatory role in the translation apparatus. It is located in the cytoplasm. The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases, such as systemic lupus erythematosus. As is typical

Gene Name: RPL7

Protein Name: 60S ribosomal protein L7

Molecular Weight: 29 kDa

Gene ID: 6129

OMIM: 604166

UniProt: P18124