ABHD4 antibody (AA 251-300)

Catalog No. ABIN1534584

This Rabbit Polyclonal antibody specifically detects ABHD4 in ELISA, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for ABHD4 antibody (AA 251-300) (ABIN1534584)

Target: ABHD4 (Abhydrolase Domain Containing 4 (ABHD4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABHD4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ABHD4 Antibody

Binding Specificity: AA 251-300

Purpose: ABHD4 Antibody

Specificity: ABHD4 Polyclonal Antibody detects endogenous levels of ABHD4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ABHD4. AA range:251-300

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ABHD4

Target: ABHD4 (Abhydrolase Domain Containing 4 (ABHD4))

Alternative Name: ABHD4

Background:

Synonyms: ABHD4, Abhydrolase domain-containing protein 4, Alpha/beta-hydrolase 4, Lyso-N-acylphosphatidylethanolamine lipase

Background: caution:Thr-291 is present instead of the conserved His which is expected to be an active site residue.,function:Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.,similarity:Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.,

Gene Name: ABHD4

Protein Name: Abhydrolase domain-containing protein 4

Molecular Weight: 38 kDa

Gene ID: 63874

UniProt: Q8TB40