ACER3 antibody (AA 171-220)

Catalog No. ABIN1534621

The Rabbit Polyclonal anti-ACER3 antibody is suitable to detect ACER3 in samples from Human and Mouse. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for ACER3 antibody (AA 171-220) (ABIN1534621)

Target: ACER3 (Alkaline Ceramidase 3 (ACER3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACER3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ACER3 Antibody

Binding Specificity: AA 171-220

Purpose: APHC Antibody

Specificity: APHC Polyclonal Antibody detects endogenous levels of APHC protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PHCA. AA range:171-220

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ACER3

Target: ACER3 (Alkaline Ceramidase 3 (ACER3))

Alternative Name: PHCA

Background:

Synonyms: ACER3, APHC, PHCA, Alkaline ceramidase 3, AlkCDase 3, Alkaline CDase 3, Alkaline dihydroceramidase SB89, Alkaline phytoceramidase, aPHC

Background: enzyme regulation:Activated by Ca(2+) and inhibited by Zn(2+).,function:Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity.,similarity:Belongs to the alkaline ceramidase family.,tissue specificity:Ubiquitously expressed. Highest expression in placenta.,

Gene Name: ACER3

Protein Name: Alkaline ceramidase 3

Molecular Weight: 31 kDa

Gene ID: 55331

UniProt: Q9NUN7