CHST8 antibody (AA 341-390)

Catalog No. ABIN485340

The Rabbit Polyclonal anti-CHST8 antibody (ABIN485340) specifically detects CHST8 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CHST8 antibody (AA 341-390) (ABIN485340)

Target: CHST8 (Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 8 (CHST8))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHST8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CHST8 Antibody

Binding Specificity: AA 341-390

Purpose: GalNAc4ST-1 Antibody

Specificity: GalNAc4ST-1 Polyclonal Antibody detects endogenous levels of GalNAc4ST-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CHST8. AA range:341-390

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CHST8

Target: CHST8 (Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 8 (CHST8))

Alternative Name: CHST8

Background:

Synonyms: CHST8, Carbohydrate sulfotransferase 8, GalNAc-4-O-sulfotransferase 1, GalNAc-4-ST1, GalNAc4ST-1, N-acetylgalactosamine-4-O-sulfotransferase 1

Background: The protein encoded by this gene belongs to the sulfotransferase 2 family. It is predominantly expressed in the pituitary gland, and is localized to the golgi membrane. This protein catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. It is responsible for sulfation of GalNAc on luteinizing hormone (LH), which is required for production of the sex hormones. Mice lacking this enzyme, exhibit increased levels of circulating LH, and precocious sexual maturation of both male and female mice. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011],

Gene Name: CHST8

Protein Name: Carbohydrate sulfotransferase 8

Molecular Weight: 48 kDa

Gene ID: 64377

OMIM: 610190

UniProt: Q9H2A9