CA14 antibody (AA 161-210)

Catalog No. ABIN1534726

The Rabbit Polyclonal anti-CA14 antibody is suitable to detect CA14 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for CA14 antibody (AA 161-210) (ABIN1534726)

Target: CA14 (Carbonic Anhydrase XIV (CA14))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CA14 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CA14 Antibody

Binding Specificity: AA 161-210

Purpose: CA XIV Antibody

Specificity: CA XIV Polyclonal Antibody detects endogenous levels of CA XIV protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CA14. AA range:161-210

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CA14

Target: CA14 (Carbonic Anhydrase XIV (CA14))

Alternative Name: CA14

Background:

Synonyms: CA14, Carbonic anhydrase 14, Carbonate dehydratase XIV, Carbonic anhydrase XIV, CA-XIV

Background: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XIV is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform, CA XII, however, they have different patterns of tissue-specific expression and thus may play different physiologic roles. [provided by RefSeq, Jul 2008],

Gene Name: CA14

Protein Name: Carbonic anhydrase 14

Molecular Weight: 37 kDa

Gene ID: 23632

OMIM: 604832

UniProt: Q9ULX7