ATG4C antibody (AA 21-70)

Catalog No. ABIN1534813

The Rabbit Polyclonal anti-ATG4C antibody is suitable to detect ATG4C in samples from Human and Monkey. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for ATG4C antibody (AA 21-70) (ABIN1534813)

Target: ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG4C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-ATG4C Antibody

Binding Specificity: AA 21-70

Purpose: Atg4C Antibody

Specificity: Atg4C Polyclonal Antibody detects endogenous levels of Atg4C protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ATG4C. AA range:21-70

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ATG4C

Target: ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))

Alternative Name: ATG4C

Background:

Synonyms: ATG4C, APG4C, AUTL1, AUTL3, Cysteine protease ATG4C, AUT-like 3 cysteine endopeptidase, Autophagin-3, Autophagy-related cysteine endopeptidase 3, Autophagy-related protein 4 homolog C

Background: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed.This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. [provided by RefSeq, Jul 2008],

Gene Name: ATG4C

Protein Name: Cysteine protease ATG4C

Molecular Weight: 52 kDa

Gene ID: 84938

OMIM: 611339

UniProt: Q96DT6

Pathways: Autophagy