GBA3 antibody (AA 291-340)

Catalog No. ABIN1534816

The Rabbit Polyclonal anti-GBA3 antibody is suitable to detect GBA3 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for GBA3 antibody (AA 291-340) (ABIN1534816)

Target: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBA3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GBA3 Antibody

Binding Specificity: AA 291-340

Purpose: CBG Antibody

Specificity: CBG Polyclonal Antibody detects endogenous levels of CBG protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GBA3. AA range:291-340

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GBA3

Target: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Alternative Name: GBA3

Background:

Synonyms: GBA3, CBG, CBGL1, Cytosolic beta-glucosidase, Cytosolic beta-glucosidase-like protein 1

Background: The protein encoded by this gene is an enzyme that can hydrolyze several types of glycosides. This gene is a polymorphic pseudogene, with the most common allele being the functional allele that encodes the full-length protein. Some individuals, as represented by the reference genome allele, contain a single nucleotide polymorphism that results in a premature stop codon in the coding region, and therefore this allele is pseudogenic due to the failure to produce a functional full-length protein. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Mar 2013],

Gene Name: GBA3

Protein Name: Cytosolic beta-glucosidase

Molecular Weight: 53 kDa

Gene ID: 57733

OMIM: 606619

UniProt: Q9H227