PLA2G4E antibody (AA 401-450)

Catalog No. ABIN1534821

This Rabbit Polyclonal antibody specifically detects PLA2G4E in ELISA, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PLA2G4E antibody (AA 401-450) (ABIN1534821)

Target: PLA2G4E (Phospholipase A2, Group IVE (PLA2G4E))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G4E antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PLA2G4E Antibody

Binding Specificity: AA 401-450

Purpose: cPLA2-ε Antibody

Specificity: CPLA2-ε Polyclonal Antibody detects endogenous levels of cPLA2-ε protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PLA2G4E. AA range:401-450

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PLA2G4E

Target: PLA2G4E (Phospholipase A2, Group IVE (PLA2G4E))

Alternative Name: PLA2G4E

Background:

Synonyms: PLA2G4E, Cytosolic phospholipase A2 epsilon, cPLA2-epsilon, Phospholipase A2 group IVE

Background: catalytic activity:Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.,domain:The N-terminal C2 domain associates with lipid membranes and mediates its regulation by presenting the active site to its substrate in response to elevations of cytosolic Ca(2+).,enzyme regulation:Stimulated by cytosolic Ca(2+).,function:Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position.,similarity:Contains 1 C2 domain.,similarity:Contains 1 PLA2c domain.,subcellular location:Translocates to lysosomal membranes in a calcium-dependent fashion.,

Gene Name: PLA2G4E

Protein Name: Cytosolic phospholipase A2 epsilon

Molecular Weight: 95 kDa

Gene ID: 123745

UniProt: Q3MJ16

Pathways: Inositol Metabolic Process, VEGF Signaling