Desmoglein 2 antibody (AA 401-450)

Catalog No. ABIN1534829

The Rabbit Polyclonal anti-Desmoglein 2 antibody (ABIN1534829) specifically detects Desmoglein 2 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Desmoglein 2 antibody (AA 401-450) (ABIN1534829)

Target: Desmoglein 2 (DSG2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Desmoglein 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Desmoglein 2 Antibody

Binding Specificity: AA 401-450

Purpose: Dsg2 Antibody

Specificity: Dsg2 Polyclonal Antibody detects endogenous levels of Dsg2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human DSG2. AA range:401-450

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Desmoglein 2

Target: Desmoglein 2 (DSG2)

Alternative Name: DSG2

Background:

Synonyms: DSG2, CDHF5, Desmoglein-2, Cadherin family member 5, HDGC

Background: This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016],

Gene Name: DSG2

Protein Name: Desmoglein-2

Molecular Weight: 122 kDa

Gene ID: 1829

OMIM: 125671

UniProt: Q14126

Pathways: Cell-Cell Junction Organization