DNAI1 antibody (AA 211-260)

Catalog No. ABIN1534853

The Rabbit Polyclonal anti-DNAI1 antibody (ABIN1534853) specifically detects DNAI1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for DNAI1 antibody (AA 211-260) (ABIN1534853)

Target: DNAI1 (Dynein, Axonemal, Intermediate Chain 1 (DNAI1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNAI1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DNAI1 Antibody

Binding Specificity: AA 211-260

Purpose: Dynein IC1 Antibody

Specificity: Dynein IC1 Polyclonal Antibody detects endogenous levels of Dynein IC1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human DNAI1. AA range:211-260

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for DNAI1

Target: DNAI1 (Dynein, Axonemal, Intermediate Chain 1 (DNAI1))

Alternative Name: DNAI1

Background:

Synonyms: DNAI1, Dynein intermediate chain 1, axonemal, Axonemal dynein intermediate chain 1

Background: This gene encodes a member of the dynein intermediate chain family. The encoded protein is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

Gene Name: DNAI1

Protein Name: Dynein intermediate chain 1 axonemal

Molecular Weight: 79 kDa

Gene ID: 27019

OMIM: 244400

UniProt: Q9UI46