GJB7 antibody (AA 21-70)

Catalog No. ABIN1534933

The Rabbit Polyclonal anti-GJB7 antibody is suitable to detect GJB7 in samples from Human, Rat and Mouse. It has been validated for ELISA and WB.

Quick Overview for GJB7 antibody (AA 21-70) (ABIN1534933)

Target: GJB7 (GJb7) (Gap Junction Protein, beta 7, 25kDa (GJb7))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJB7 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-GJB7 Antibody

Binding Specificity: AA 21-70

Purpose: Connexin 25 Antibody

Specificity: Connexin 25 Polyclonal Antibody detects endogenous levels of Connexin 25 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GJB7. AA range:21-70

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GJB7

Target: GJB7 (GJb7) (Gap Junction Protein, beta 7, 25kDa (GJb7))

Alternative Name: GJB7

Background:

Synonyms: GJB7, CX25, Gap junction beta-7 protein, Connexin-25, Cx25

Background: Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008],

Gene Name: GJB7

Protein Name: Gap junction beta-7 protein

Molecular Weight: 25 kDa

Gene ID: 375519

OMIM: 611921

UniProt: Q6PEY0