ERAS antibody (AA 184-233)

Catalog No. ABIN1534957

The Rabbit Polyclonal anti-ERAS antibody is suitable to detect ERAS in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IF.

Quick Overview for ERAS antibody (AA 184-233) (ABIN1534957)

Target: ERAS (ES cell expressed Ras (ERAS))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERAS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-ERAS Antibody

Binding Specificity: AA 184-233

Purpose: E-Ras Antibody

Specificity: E-Ras Polyclonal Antibody detects endogenous levels of E-Ras protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ERAS. AA range:184-233

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ERAS

Target: ERAS (ES cell expressed Ras (ERAS))

Alternative Name: ERAS

Background:

Synonyms: ERAS, HRAS2, HRASP, GTPase ERas, E-Ras, Embryonic stem cell-expressed Ras

Background: This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance. [provided by RefSeq, Dec 2012],

Gene Name: ERAS

Protein Name: GTPase Eras

Molecular Weight: 25 kDa

Gene ID: 3266

OMIM: 300437

UniProt: Q7Z444