LRRC41 antibody (AA 391-440)

Catalog No. ABIN1535000

The Rabbit Polyclonal anti-LRRC41 antibody (ABIN1535000) specifically detects LRRC41 in WB, ELISA, IHC and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for LRRC41 antibody (AA 391-440) (ABIN1535000)

Target: LRRC41 (Leucine Rich Repeat Containing 41 (LRRC41))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC41 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-LRRC41 Antibody

Binding Specificity: AA 391-440

Purpose: LRRC41 Antibody

Specificity: LRRC41 Polyclonal Antibody detects endogenous levels of LRRC41 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human LRRC41. AA range:391-440

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for LRRC41

Target: LRRC41 (Leucine Rich Repeat Containing 41 (LRRC41))

Alternative Name: LRRC41

Background:

Synonyms: LRRC41, MUF1, PP7759, Leucine-rich repeat-containing protein 41, Protein Muf1

Background: caution:It is uncertain whether Met-1 or Met-23 is the initiator.,domain:The elongin BC complex binding domain is also known as BC-box with the consensus [APST]-L-x(3)-C-x(3)-[AILV].,function:Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification, protein ubiquitination.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Translation N-terminally extended.,similarity:Contains 7 LRR (leucine-rich) repeats.,subunit:Part of an E3 ubiquitin-protein ligase complex with Elongin BC (TCEB1 and TCEB2), RBX1 and CUL5. Component of a probable ECS(LRRC41) complex which contains CUL5, RNF7/RBX2, Elongin BC and LRRC41. Interacts with CUL5, RNF7, TCEB1 and TCEB2.,

Gene Name: LRRC41

Protein Name: Leucine-rich repeat-containing protein 41

Molecular Weight: 88 kDa

Gene ID: 10489

UniProt: Q15345