LAMP3 antibody (AA 274-323)

Catalog No. ABIN1535014

The Rabbit Polyclonal anti-LAMP3 antibody is suitable to detect LAMP3 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IF (p) and IHC (p).

Quick Overview for LAMP3 antibody (AA 274-323) (ABIN1535014)

Target: LAMP3 (Lysosomal-Associated Membrane Protein 3 (LAMP3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAMP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-LAMP3 Antibody

Binding Specificity: AA 274-323

Purpose: DC-LAMP Antibody

Specificity: DC-LAMP Polyclonal Antibody detects endogenous levels of DC-LAMP protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human LAMP3. AA range:274-323

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for LAMP3

Target: LAMP3 (Lysosomal-Associated Membrane Protein 3 (LAMP3))

Alternative Name: LAMP3

Background:

Synonyms: LAMP3, DCLAMP, TSC403, Lysosome-associated membrane glycoprotein 3, LAMP-3, Lysosomal-associated membrane protein 3, DC-lysosome-associated membrane glycoprotein, DC LAMP, Protein TSC403, CD antigen CD208

Background: MET proto-oncogene, receptor tyrosine kinase(MET) Homo sapiens This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016],

Gene Name: LAMP3

Protein Name: Lysosome-associated membrane glycoprotein 3

Molecular Weight: 44 kDa

OMIM: 605883

UniProt: Q9UQV4