MNDA antibody (AA 358-407)

Catalog No. ABIN1535045

The Rabbit Polyclonal anti-MNDA antibody (ABIN1535045) specifically detects MNDA in WB, ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MNDA antibody (AA 358-407) (ABIN1535045)

Target: MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MNDA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MNDA Antibody

Binding Specificity: AA 358-407

Purpose: MNDA Antibody

Specificity: MNDA Polyclonal Antibody detects endogenous levels of MNDA protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MNDA. AA range:358-407

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MNDA

Target: MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))

Alternative Name: MNDA

Background:

Synonyms: MNDA, Myeloid cell nuclear differentiation antigen

Background: The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. [provided by RefSeq, Jul 2008],

Gene Name: MNDA

Protein Name: Myeloid cell nuclear differentiation antigen

Molecular Weight: 45 kDa

Gene ID: 4332

OMIM: 159553

UniProt: P41218