MYBPC3 antibody (AA 329-378)

Catalog No. ABIN1535052

This Rabbit Polyclonal antibody specifically detects MYBPC3 in ELISA, IHC (p) and IF (p). It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for MYBPC3 antibody (AA 329-378) (ABIN1535052)

Target: MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYBPC3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-MYBPC3 Antibody

Binding Specificity: AA 329-378

Purpose: MYBPC3 Antibody

Specificity: MYBPC3 Polyclonal Antibody detects endogenous levels of MYBPC3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MYBPC3. AA range:329-378

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MYBPC3

Target: MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))

Alternative Name: MYBPC3

Background:

Synonyms: MYBPC3, Myosin-binding protein C, cardiac-type, Cardiac MyBP-C, C-protein, cardiac muscle isoform

Background: tumor protein p53(TP53) Homo sapiens This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013],

Gene Name: MYBPC3

Protein Name: Myosin-binding protein C cardiac-type

Molecular Weight: 140 kDa

OMIM: 115197

UniProt: Q14896