NOX3 antibody (AA 287-336)

Catalog No. ABIN1535076

This Rabbit Polyclonal antibody specifically detects NOX3 in ELISA, WB, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.It has been mentioned in 1 publication

Quick Overview for NOX3 antibody (AA 287-336) (ABIN1535076)

Target: NOX3 (NADPH Oxidase 3 (NOX3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOX3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-NOX3 Antibody

Binding Specificity: AA 287-336

Purpose: Nox3 Antibody

Specificity: Nox3 Polyclonal Antibody detects endogenous levels of Nox3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human NOX3. AA range:287-336

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

References for anti-NOX3 antibody (ABIN1535076)

Du, Yang, Hu, Sun, Zhang, Peng, Zhong, Huang, Kong: "A long-term high-fat diet increases oxidative stress, mitochondrial damage and apoptosis in the inner ear of D-galactose-induced aging rats." in: Hearing research, Vol. 287, Issue 1-2, pp. 15-24, (2012) (PubMed).

Target Details for NOX3

Target: NOX3 (NADPH Oxidase 3 (NOX3))

Alternative Name: NOX3

Background:

Synonyms: NOX3, MOX2, NADPH oxidase 3, Mitogenic oxidase 2, MOX-2, gp91phox homolog 3, GP91-3

Background: This gene encodes a member of the NOX family of NADPH oxidases. These enzymes have the capacity to generate superoxide and other reactive oxygen species (ROS) and transport electrons across the plasma membrane. The ROS generated by family members have been implicated in numerous biological functions including host defense, posttranlational processing of proteins, cellular signaling, regulation of gene expression, and cell differentiation.The protein encoded by this gene is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity.[provided by RefSeq, May 2009],

Gene Name: NOX3

Protein Name: NADPH oxidase 3

Molecular Weight: 64 kDa

Gene ID: 50508

OMIM: 607105

UniProt: Q9HBY0