NCOA7 antibody (AA 422-471)

Catalog No. ABIN1535121

This Rabbit Polyclonal antibody specifically detects NCOA7 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for NCOA7 antibody (AA 422-471) (ABIN1535121)

Target: NCOA7 (Nuclear Receptor Coactivator 7 (NCOA7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCOA7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-NCOA7 Antibody

Binding Specificity: AA 422-471

Purpose: NCoA-7 Antibody

Specificity: NCoA-7 Polyclonal Antibody detects endogenous levels of NCoA-7 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human NCOA7. AA range:422-471

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NCOA7

Target: NCOA7 (Nuclear Receptor Coactivator 7 (NCOA7))

Alternative Name: NCOA7

Background:

Synonyms: NCOA7, ERAP140, ESNA1, Nbla00052, Nbla10993, Nuclear receptor coactivator 7, 140 kDa estrogen receptor-associated protein, Estrogen nuclear receptor coactivator 1

Background: function:Enhances the transcriptional activities of several nuclear receptors. Involved in the coactivation of different nuclear receptors, such as ESR1, THRB, PPARG and RARA.,similarity:Belongs to the OXR1 family.,similarity:Contains 1 LysM repeat.,similarity:Contains 1 TLD domain.,subunit:Interacts with ESR1, ESR2A, ESR2B, THRB, PPARG and RARA in a ligand-inducible manner. Interacts with the heterodimer AHR-ARNT.,tissue specificity:Highly expressed in brain. Weakly expressed in mammary gland, ovary, uterus, prostate, stomach, bladder, spinal cord and pancreas. Expressed in cancer cell line.,

Gene Name: NCOA7

Protein Name: Nuclear receptor coactivator 7

Molecular Weight: 106 kDa

Gene ID: 135112

OMIM: 609752

UniProt: Q8NI08

Pathways: Nuclear Hormone Receptor Binding