EHHADH antibody (AA 476-525)

Catalog No. ABIN1535147

The Rabbit Polyclonal anti-EHHADH antibody (ABIN1535147) specifically detects EHHADH in WB, ELISA, IHC and IF. The antibody is reactive with Human and Rat samples.

Quick Overview for EHHADH antibody (AA 476-525) (ABIN1535147)

Target: EHHADH (Enoyl-CoA, Hydratase/3-Hydroxyacyl CoA Dehydrogenase (EHHADH))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EHHADH antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-EHHADH Antibody

Binding Specificity: AA 476-525

Purpose: PBFE Antibody

Specificity: PBFE Polyclonal Antibody detects endogenous levels of PBFE protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human EHHADH. AA range:476-525

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for EHHADH

Target: EHHADH (Enoyl-CoA, Hydratase/3-Hydroxyacyl CoA Dehydrogenase (EHHADH))

Alternative Name: EHHADH

Background:

Synonyms: EHHADH, ECHD, Peroxisomal bifunctional enzyme, PBE, PBFE

Background: catalytic activity:(3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H(2)O.,catalytic activity:(3Z)-dodec-3-enoyl-CoA = (2E)-dodec-2-enoyl-CoA.,catalytic activity:(S)-3-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA + NADH.,disease:Absent in patients suffering with peroxisomal disorders such as Zellweger syndrome, neonatal adrenoleukodystrophy and infantile Refsum disease.,pathway:Lipid metabolism, fatty acid beta-oxidation.,similarity:In the C-terminal section, belongs to the 3-hydroxyacyl-CoA dehydrogenase family.,similarity:In the N-terminal section, belongs to the enoyl-CoA hydratase/isomerase family.,subunit:Monomer.,tissue specificity:Liver and kidney. Lower amounts seen in the brain.,

Gene Name: EHHADH

Protein Name: Peroxisomal bifunctional enzyme

Molecular Weight: 79 kDa

Gene ID: 1962

OMIM: 607037

UniProt: Q08426

Pathways: Monocarboxylic Acid Catabolic Process