RAB6A antibody (AA 113-162)

Catalog No. ABIN1535278

The Rabbit Polyclonal anti-RAB6A antibody is suitable to detect RAB6A in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for RAB6A antibody (AA 113-162) (ABIN1535278)

Target: RAB6A (RAB6A, Member RAS Oncogene Family (RAB6A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB6A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-RAB6A Antibody

Binding Specificity: AA 113-162

Purpose: Rab 6A Antibody

Specificity: Rab 6A Polyclonal Antibody detects endogenous levels of Rab 6A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human RAB6A. AA range:113-162

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for RAB6A

Target: RAB6A (RAB6A, Member RAS Oncogene Family (RAB6A))

Alternative Name: RAB6A

Background:

Synonyms: RAB6A, RAB6, Ras-related protein Rab-6A, Rab-6

Background: This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011],

Gene Name: RAB6A

Protein Name: Ras-related protein Rab-6A

Molecular Weight: 23 kDa

Gene ID: 5870

OMIM: 179513

UniProt: P20340