Septin 2 antibody (AA 103-152)

Catalog No. ABIN1535327

The Rabbit Polyclonal anti-Septin 2 antibody (ABIN1535327) specifically detects Septin 2 in WB and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Septin 2 antibody (AA 103-152) (ABIN1535327)

Target: Septin 2 (SEPT2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Septin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Septin 2 Antibody

Binding Specificity: AA 103-152

Purpose: Septin 2 Antibody

Specificity: Septin 2 Polyclonal Antibody detects endogenous levels of Septin 2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human SEPT2. AA range:103-152

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Septin 2

Target: Septin 2 (SEPT2)

Alternative Name: SEPT2

Background:

Synonyms: SEPT2, DIFF6, KIAA0158, NEDD5, Septin-2, Neural precursor cell expressed developmentally down-regulated protein 5, NEDD-5

Background: function:Required for normal progress through mitosis. Involved in cytokinesis.,similarity:Belongs to the septin family.,subcellular location:Accumulates near the contractile ring from anaphase through telophase, and finally condenses into the midbody. In interphase and postmitotic cells, localised to fibrous or granular structures, depending on the growth state of the cell.,subunit:Monomer, and homodimer. Nucleotide binding promotes dimerization. Heterohexamer composed of two heterotrimers containing one copy each of SEPT2, SEPT6 and SEPT7. The asymmetrical heterotrimers associate head-to-head to form a hexameric unit that assembles into filaments.,

Gene Name: SEPT2

Protein Name: Septin-2

Molecular Weight: 41 kDa

Gene ID: 4735

OMIM: 601506

UniProt: Q15019