SIRPB1 antibody (AA 231-280)

Catalog No. ABIN1535372

The Rabbit Polyclonal anti-SIRPB1 antibody (ABIN1535372) specifically detects SIRPB1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SIRPB1 antibody (AA 231-280) (ABIN1535372)

Target: SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRPB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SIRPB1 Antibody

Binding Specificity: AA 231-280

Purpose: CD172b Antibody

Specificity: CD172b Polyclonal Antibody detects endogenous levels of CD172b protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human SIRPB1. AA range:231-280

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SIRPB1

Target: SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))

Alternative Name: SIRPB1

Background:

Synonyms: SIRPB1, Signal-regulatory protein beta-1, SIRP-beta-1, CD172 antigen-like family member B, CD antigen CD172b

Background: The protein encoded byThis gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009],

Gene Name: SIRPB1

Protein Name: Signal-regulatory protein beta-1

Molecular Weight: 43 kDa

Gene ID: 10326

OMIM: 603889

UniProt: O00241