YOD1 antibody (AA 116-165)

Catalog No. ABIN1535443

The Rabbit Polyclonal anti-YOD1 antibody is suitable to detect YOD1 in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for YOD1 antibody (AA 116-165) (ABIN1535443)

Target: YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YOD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-YOD1 Antibody

Binding Specificity: AA 116-165

Purpose: OTUD2 Antibody

Specificity: OTUD2 Polyclonal Antibody detects endogenous levels of OTUD2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human YOD1. AA range:116-165

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for YOD1

Target: YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))

Alternative Name: YOD1

Background:

Synonyms: YOD1, DUBA8, HIN7, OTUD2, Ubiquitin thioesterase OTU1, DUBA-8, HIV-1-induced protease 7, HIN-7, HsHIN7, OTU domain-containing protein 2

Background: Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates.The protein encoded by this gene belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013],

Gene Name: YOD1

Protein Name: Ubiquitin thioesterase OTU1

Molecular Weight: 38 kDa

Gene ID: 55432

OMIM: 612023

UniProt: Q5VVQ6

Pathways: ER-Nucleus Signaling