CysLTR1 antibody (AA 131-180)

Catalog No. ABIN1535582

The Rabbit Polyclonal anti-CysLTR1 antibody (ABIN1535582) specifically detects CysLTR1 in WB, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CysLTR1 antibody (AA 131-180) (ABIN1535582)

Target: CysLTR1 (CYSLTR1) (Cysteinyl Leukotriene Receptor 1 (CYSLTR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CysLTR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-CysLTR1 Antibody

Binding Specificity: AA 131-180

Purpose: CysLTR1 Antibody

Specificity: CysLTR1 Polyclonal Antibody detects endogenous levels of CysLTR1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CYSLTR1. AA range:131-180

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CysLTR1

Target: CysLTR1 (CYSLTR1) (Cysteinyl Leukotriene Receptor 1 (CYSLTR1))

Alternative Name: CYSLTR1

Background:

Synonyms: CYSLTR1, CYSLT1, Cysteinyl leukotriene receptor 1, CysLTR1, Cysteinyl leukotriene D4 receptor, LTD4 receptor, G-protein coupled receptor HG55, HMTMF81

Background: This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],

Gene Name: CYSLTR1

Protein Name: Cysteinyl leukotriene receptor 1

Molecular Weight: 38 kDa

Gene ID: 10800

OMIM: 300201

UniProt: Q9Y271