GPR17 antibody (AA 196-245)

Catalog No. ABIN1535634

This Rabbit Polyclonal antibody specifically detects GPR17 in WB, ELISA and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for GPR17 antibody (AA 196-245) (ABIN1535634)

Target: GPR17 (G Protein-Coupled Receptor 17 (GPR17))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-GPR17 Antibody

Binding Specificity: AA 196-245

Purpose: GPR17 Antibody

Specificity: GPR17 Polyclonal Antibody detects endogenous levels of GPR17 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GPR17. AA range:196-245

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GPR17

Target: GPR17 (G Protein-Coupled Receptor 17 (GPR17))

Alternative Name: GPR17

Background:

Synonyms: GPR17, Uracil nucleotide/cysteinyl leukotriene receptor, UDP/CysLT receptor, G-protein coupled receptor 17, P2Y-like receptor, R12

Background: function:Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.,

Gene Name: GPR17

Protein Name: Uracil nucleotide/cysteinyl leukotriene receptor

Molecular Weight: 40 kDa

Gene ID: 2840

OMIM: 603071

UniProt: Q13304