ADORA1 antibody (AA 277-326)

Catalog No. ABIN1535640

This Rabbit Polyclonal antibody specifically detects ADORA1 in WB, ELISA and IF. It exhibits reactivity toward Human and Rat.

Quick Overview for ADORA1 antibody (AA 277-326) (ABIN1535640)

Target: ADORA1 (Adenosine A1 Receptor (ADORA1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADORA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-ADORA1 Antibody

Binding Specificity: AA 277-326

Purpose: Adenosine A1-R Antibody

Specificity: Adenosine A1-R Polyclonal Antibody detects endogenous levels of Adenosine A1-R protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ADORA1. AA range:277-326

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ADORA1

Target: ADORA1 (Adenosine A1 Receptor (ADORA1))

Alternative Name: ADORA1

Background:

Synonyms: ADORA1; Adenosine receptor A1

Background: The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008],

Gene Name: ADORA1

Protein Name: Adenosine receptor A1

Molecular Weight: 36 kDa

Gene ID: 134

OMIM: 102775

UniProt: P30542

Pathways: EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Synaptic Membrane