BDKRB1 antibody (AA 201-250)

Catalog No. ABIN1535653

The Rabbit Polyclonal anti-BDKRB1 antibody is suitable to detect BDKRB1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IF.

Quick Overview for BDKRB1 antibody (AA 201-250) (ABIN1535653)

Target: BDKRB1 (Bradykinin Receptor B1 (BDKRB1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BDKRB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-BDKRB1 Antibody

Binding Specificity: AA 201-250

Purpose: Bradykinin B1 R Antibody

Specificity: Bradykinin B1 R Polyclonal Antibody detects endogenous levels of Bradykinin B1 R protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human BDKRB1. AA range:201-250

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BDKRB1

Target: BDKRB1 (Bradykinin Receptor B1 (BDKRB1))

Alternative Name: BDKRB1

Background:

Synonyms: BDKRB1, BRADYB1, B1 bradykinin receptor, B1R, BK-1 receptor

Background: Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions.The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],

Gene Name: BDKRB1

Protein Name: B1 bradykinin receptor

Molecular Weight: 40 kDa

Gene ID: 623

OMIM: 600337

UniProt: P46663

Pathways: ACE Inhibitor Pathway