CNR2 antibody (AA 191-240)

Catalog No. ABIN1535662

The Rabbit Polyclonal anti-CNR2 antibody is suitable to detect CNR2 in samples from Human, Rat and Mouse. It has been validated for WB, ELISA and IF.

Quick Overview for CNR2 antibody (AA 191-240) (ABIN1535662)

Target: CNR2 (Cannabinoid Receptor 2 (CNR2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-CNR2 Antibody

Binding Specificity: AA 191-240

Purpose: CB2 Antibody

Specificity: CB2 Polyclonal Antibody detects endogenous levels of CB2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CNR2. AA range:191-240

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CNR2

Target: CNR2 (Cannabinoid Receptor 2 (CNR2))

Alternative Name: CNR2

Background:

Synonyms: CNR2, Cannabinoid receptor 2, CB-2, CB2, hCB2, CX5

Background: The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008],

Gene Name: CNR2

Protein Name: Cannabinoid receptor 2

Molecular Weight: 39 kDa

Gene ID: 1269

OMIM: 605051

UniProt: P34972