FZD8 antibody (AA 486-535)

Catalog No. ABIN1535685

This Rabbit Polyclonal antibody specifically detects FZD8 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for FZD8 antibody (AA 486-535) (ABIN1535685)

Target: FZD8 (Frizzled Family Receptor 8 (FZD8))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-FZD8 Antibody

Binding Specificity: AA 486-535

Purpose: Frizzled-8 Antibody

Specificity: Frizzled-8 Polyclonal Antibody detects endogenous levels of Frizzled-8 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human FZD8. AA range:486-535

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for FZD8

Target: FZD8 (Frizzled Family Receptor 8 (FZD8))

Alternative Name: FZD8

Background:

Synonyms: FZD8, Frizzled-8, Fz-8, hFz8

Background: frizzled class receptor 8(FZD8) Homo sapiens This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008],

Gene Name: FZD8

Protein Name: Frizzled-8

Molecular Weight: 73 kDa

Gene ID: 8325

OMIM: 606146

UniProt: Q9H461

Pathways: WNT Signaling