Galanin Receptor 1 antibody (AA 161-210)

Catalog No. ABIN1535689

The Rabbit Polyclonal anti-Galanin Receptor 1 antibody is suitable to detect Galanin Receptor 1 in samples from Human and Mouse. It has been validated for ELISA and IF.

Quick Overview for Galanin Receptor 1 antibody (AA 161-210) (ABIN1535689)

Target: Galanin Receptor 1 (GALR1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Galanin Receptor 1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-Galanin Receptor 1 Antibody

Binding Specificity: AA 161-210

Purpose: GALR1 Antibody

Specificity: GALR1 Polyclonal Antibody detects endogenous levels of GALR1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GALR1. AA range:161-210

Isotype: IgG

Application Details

Application Notes: IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Galanin Receptor 1

Target: Galanin Receptor 1 (GALR1)

Alternative Name: GALR1

Background:

Synonyms: GALR1, GALNR, GALNR1, Galanin receptor type 1, GAL1-R, GALR-1

Background: The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008],

Gene Name: GALR1

Protein Name: Galanin receptor type 1

Molecular Weight: 38 kDa

Gene ID: 2587

OMIM: 600377

UniProt: P47211

Pathways: cAMP Metabolic Process