NPY5R antibody (AA 221-270)

Catalog No. ABIN1535790

This Rabbit Polyclonal antibody specifically detects NPY5R in WB, IHC, IF and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for NPY5R antibody (AA 221-270) (ABIN1535790)

Target: NPY5R (Neuropeptide Y Receptor Y5 (NPY5R))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPY5R antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Product Details anti-NPY5R Antibody

Binding Specificity: AA 221-270

Purpose: NPY5-R Antibody

Specificity: NPY5-R Polyclonal Antibody detects endogenous levels of NPY5-R protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human NPY5R. AA range:221-270

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NPY5R

Target: NPY5R (Neuropeptide Y Receptor Y5 (NPY5R))

Alternative Name: NPY5R

Background:

Synonyms: NPY5R, NPYR5, Neuropeptide Y receptor type 5, NPY5-R, NPY-Y5 receptor, NPYY5-R, Y5 receptor

Background: The protein encoded by this gene is a receptor for neuropeptide Y and peptide YY. The encoded protein appears to be involved in regulating food intake, with defects in this gene being associated with eating disorders. Also, the encoded protein is involved in a pathway that protects neuroblastoma cells from chemotherapy-induced cell death, providing a possible therapeutic target against neuroblastoma. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2015],

Gene Name: NPY5R

Protein Name: Neuropeptide Y receptor type 5

Molecular Weight: 51 kDa

Gene ID: 4889

OMIM: 602001

UniProt: Q15761

Pathways: Feeding Behaviour