PEVR1 (AA 43-92) antibody

Catalog No. ABIN1535981

The Rabbit Polyclonal anti-PEVR1 antibody (ABIN1535981) specifically detects PEVR1 in WB, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PEVR1 (AA 43-92) antibody (ABIN1535981)

Target: PEVR1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details

Binding Specificity: AA 43-92

Purpose: GPR172A Antibody

Specificity: GPR172A Polyclonal Antibody detects endogenous levels of GPR172A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PEVR1. AA range:43-92

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details

Target: PEVR1

Background:

Synonyms: SLC52A2, GPR172A, PAR1, RFT3, Solute carrier family 52, riboflavin transporter, member 2, Porcine endogenous retrovirus A receptor 1, PERV-A receptor 1, Protein GPR172A, Riboflavin transporter 3, hRFT3

Background: This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunctio

Gene Name: SLC52A2

Protein Name: Solute carrier family 52 riboflavin transporter member 2

Molecular Weight: 45 kDa

Gene ID: 79581

OMIM: 607882

UniProt: Q9HAB3