TMEM145 antibody (AA 58-107)

Catalog No. ABIN1536011

The Rabbit Polyclonal anti-TMEM145 antibody (ABIN1536011) specifically detects TMEM145 in WB, IHC, ELISA and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for TMEM145 antibody (AA 58-107) (ABIN1536011)

Target: TMEM145 (Transmembrane Protein 145 (TMEM145))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM145 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-TMEM145 Antibody

Binding Specificity: AA 58-107

Purpose: TMEM145 Antibody

Specificity: TMEM145 Polyclonal Antibody detects endogenous levels of TMEM145 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human TMEM145. AA range:58-107

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TMEM145

Target: TMEM145 (Transmembrane Protein 145 (TMEM145))

Alternative Name: TMEM145

Background:

Synonyms: TMEM145, Transmembrane protein 145

Background: TMEM145 (transmembrane protein 145) is a 493 amino acid protein encoded by a gene mapping to human chromosome 19. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2 % of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fcα receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3.

Gene Name: TMEM145

Protein Name: Transmembrane protein 145

Molecular Weight: 55 kDa

Gene ID: 284339

UniProt: Q8NBT3