Notch1 antibody (Cleaved-Val1754)

Catalog No. ABIN1536094

The Rabbit Polyclonal anti-Notch1 antibody has been validated for WB, ELISA and IHC. It is suitable to detect Notch1 in samples from Human, Mouse and Rat.

Quick Overview for Notch1 antibody (Cleaved-Val1754) (ABIN1536094)

Target: Notch1 (NOTCH1) (Notch 1 (NOTCH1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Notch1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Notch1 Antibody

Binding Specificity: AA 1735-1784, Cleaved-Val1754

Specificity:

Notch 1 (Cleaved-Val1754) Antibody detects endogenous levels of fragment of activated Notch 1 resulting from cleavage adjacent to Val1754.

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Notch 1.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:5000

Comment:

Unigene-Number: Hs.495473 (NCBI Gene Symbol: NOTCH1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for Notch1

Target: Notch1 (NOTCH1) (Notch 1 (NOTCH1))

Alternative Name: Notch 1

Background:

Synonyms: neurogenic locus notch 1, NOTC1, notch 1 (translocation-associated), Notch homolog 1, translocation-associated (Drosophila) (TAN1), Notch1, TAN1, translocation-associated notch protein TAN-1

NCBI Gene Symbol: NOTCH1

Molecular Weight: 110 kDa

Gene ID: 4851

OMIM: 190198

UniProt: P46531

Pathways: Notch Signaling, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development