ADAM17 antibody (Cleaved-Arg215)

Catalog No. ABIN1536098

This anti-ADAM17 antibody is a Rabbit Polyclonal antibody detecting ADAM17 in WB and ELISA. Suitable for Human.

Quick Overview for ADAM17 antibody (Cleaved-Arg215) (ABIN1536098)

Target: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ADAM17 Antibody

Binding Specificity: AA 196-245, Cleaved-Arg215

Specificity:

ADAM 17 (Cleaved-Arg215) Antibody detects endogenous levels of fragment of activated ADAM 17 resulting from cleavage adjacent to Arg215.

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ADAM 17.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:20000

Comment:

Unigene-Number: Hs.404914 (NCBI Gene Symbol: ADAM17)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for ADAM17

Target: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Alternative Name: ADAM 17

Background:

Synonyms: ADA17, ADAM 17, CD156b antigen, CSVP, TACE, TNF-alpha convertase, TNF-alpha-converting enzyme, a disintegrin and metalloproteinase domain 17, snake venom-like protease

NCBI Gene Symbol: ADAM17

Molecular Weight: 65 kDa

Gene ID: 6868

OMIM: 603639

UniProt: P78536

Pathways: Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus